Aktuelle Publikationen
Publikationen des Jahres 2024
Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. 2024
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
Nature. 2024 Mar;627(8003):407-415. doi: 10.1038/s41586-024-07079-8(link is external). Epub 2024 Feb 21. PMID: 38383779
Brinkmann BJ, Floerchinger A, Schniederjohann C, Roider T, Coelho M, Mack N, Bruch PM, Liebers N, Dötsch S, Busch DH, Schmitt M, Neumann F, Roessner PM, Seiffert M, Dietrich S. 2024
CD20-bispecific antibodies improve response to CD19-CAR T-cells in lymphoma in-vitro and CLL in-vivo models.
Blood. 2024 May 28:blood.2023022682. doi: 10.1182/blood.2023022682(link is external). Online ahead of print. PMID: 38805637
Carr A, Mateyka LM, Scheu SJC , Bici A, Paijmans J, Reijmers RM, Dieminger N, Dildebekova S, Hamed N, Wagner K, Busch DH und D’Ippolito E. 2024
Advances in preclinical TCR characterization: leveraging cell avidity to identify functional TCRs
Biol Chem 2024 Apr 29. PMID: 38666334 DOI: 10.1515/hsz-2023-0341(link is external)
Castillo JG, DeBarge R, Mende A, Tenvooren I, Marquez DM, Straub A, Busch DH, Spitzer MH, DuPage M. 2024
A mass cytometry approach to track the evolution of T cell responses during infection and immunotherapy by paired T cell receptor repertoire and T cell differentiation state analysis.
bioRxiv [Preprint]. 2024 Jan 12:2024.01.11.575237. doi: 10.1101/2024.01.11.575237(link is external). PMID: 38260336
Drost F, Dorigatti E, Straub A, Hilgendorf P, Wagner KI, Heyer K, López Montes M, Bischl B, Busch DH, Schober K, Schubert B.
Predicting T cell receptor functionality against mutant epitopes.
Cell Genom 2024 Aug 8:100634. PMID: 39151427 doi: 10.1016/j.xgen.2024.100634(link is external).
Esser E, Schulte EC, Graf A, Karollus A, Smith NH, Michler T, Dvoretskii S, Angelov A, Sonnabend M, Peter S, Engesser C, Radonic A, Thürmer A, von Kleist M, Gebhardt F, da Costa CP, Busch DH, Muenchhoff M, Blum H, Keppler OT, Gagneur J, Protzer U. 2024
Viral genome sequencing to decipher in-hospital SARS-CoV-2 transmission events.
Sci Rep. 2024 Mar 8;14(1):5768. doi: 10.1038/s41598-024-56162-7(link is external). PMID: 38459123
Hildenbrand K, Bohnacker S, Rajeev Menon P, Kerle A, Prodjinotho UF, Hartung F, Strasser PC, Catici DAM, Rührnößl F, Haslbeck M, Schumann K, Müller SI, Prazeres da Costa C, Esser-von Bieren J, Matthias J Feige J. 2023
Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions.
Sci Adv. 2023 Oct 27;9(43):eadg6874. PMID: 37878703 PMCID: PMC10599630 doi: 10.1126/sciadv.adg6874. Epub 2023 Oct 25.
Kocher K, Moosmann C, Drost F, Schülein C, Irrgang P, Steininger P, Zhong J, Träger J, Spriewald B, Bock C, Busch DH, Bogdan C, Schubert B, Winkler TH, Tenbusch M, Schuster EM, Schober K. 2024
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual.
Lancet Infect Dis. 2024 May;24(5):e272-e274. doi: 10.1016/S1473-3099(24)00134-8(link is external). Epub 2024 Mar 4. PMID: 38452777
Lacher SB., Dörr J, de Almeida GP, Hönninger J, Bayerl F, Hirschberger A, Pedde AM, Meiser P, Ramsauer L, Rudolph TJ, Spranger N, Morotti M, Grimm AJ, Jarosch S, Oner A, Gregor L, Lesch S, Michaelides S, Fertig L, Briukhovetska D, Majed L, Stock S, Busch DH, Buchholz VR, Knolle PA, Zehn D, Dangaj Laniti D, Kobold S, Böttcher JP. 2024
PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells.
Nature. 2024 May; 629(8011):417-425. doi: 10.1038/s41586-024-07254-x(link is external). Epub 2024 Apr 24. PMID: 38658748
Li ZX, Bronny K, Formichella L, Mejías-Luque R, Burrell T, Macke L, Lang U, Vasapolli R, Hysenaj O, Stallforth I, Vieth M, You WC, Zhang Y, Suerbaum S, Schulz C, Pan KF, Gerhard M. 2024
A multiserological line assay to potentially discriminate current from past Helicobacter pylori infection.
Clin Microbiol Infect. 2024 Jan;30(1):114-121. doi: 10.1016/j.cmi.2023.10.006(link is external). Epub 2023 Oct 11. PMID: 37827383
Manske K, Dreßler L, Fräßle SP, Effenberger M, Tschulik C, Cletiu V, Benke E, Wagner M, Schober K, Müller TR, Stemberger C, Germeroth L, Busch DH, Poltorak MP. 2024
Miniaturized CAR knocked onto CD3ε extends TCR function with CAR specificity under control of endogenous TCR signaling cascade.
J Immunol Methods. 2024 Mar;526:113617. doi: 10.1016/j.jim.2024.113617(link is external). Epub 2024 Jan 11. PMID: 38215900
Pan KF, Li WQ , Zhang L, Liu WD, Ma JL, Zhang Y, Ulm K, Wang JX, Zhang L, Bajbouj M, Zhang LF, Li M, Vieth M, Quante M, Wang LH, Suchanek S, Mejías-Luque R, Xu HM, Fan XH, Han X, Liu ZC, Zhou T, Guan WX, Schmid RM, Gerhard M, Classen M, You WC. 2024
Gastric cancer prevention by community eradication of Helicobacter pylori: a cluster-randomized controlled trial.
Nat Med. 2024 Jul 30. Online ahead of print. PMID: 39079993 doi: 10.1038/s41591-024-03153-w(link is external)
Rothe K, Bachfischer T, Karapetyan S, Hapfelmeier A, Wurst M, Gleich S, Dichtl K, Schmid RM, Triebelhorn J, Wagner L, Erber J, Voit F, Burgkart R, Obermeier A, Seybold U, Busch DH, Rämer PC, Spinner CD, Schneider J. 2024
Are enterococcal bloodstream infections an independent risk factor for a poorer 5-year survival or just a marker for severity of illness?-The Munich multicentric enterococci cohort.
Microbiol Spectr. 2023 Dec 12;11(6):e0258523. doi: 10.1128/spectrum.02585-23(link is external). Epub 2023 Oct 4. PMID: 37791770
Svec M, Dötsch S, Warmuth L, Trebo M, Fräßle S, Riddell SR, Jäger U, D'Ippolito E, Busch DH. 2024
A chimeric antigen receptor-based cellular safeguard mechanism for selective in vivo depletion of engineered T cells.
Front Immunol. 2024 Jan 11;14:1268698. doi: 10.3389/fimmu.2023.1268698(link is external). eCollection 2023. PMID: 38274808
Winterhalter PM, Warmuth L, Hilgendorf P, Schuetz JM, Dötsch S, Tonn T, Cicin-Sain L MD PhD, Busch DH, Schober K. 2024
HLA reduction of human T cells facilitates generation of immunologically multi-compatible cellular products.
Blood Adv. 2024 Apr 19:bloodadvances.2023011496. doi: 10.1182/bloodadvances.2023011496(link is external). Online ahead of print. PMID: 38640254