Publikationen des Jahres 2021


Anisuzzaman, S. Frahm, U.F. Prodjinotho, S. Bhattacharjee, A. Verschoor, and C. Prazeres da Costa. 2021.

Host-Specific Serum Factors Control the Development and Survival of Schistosoma mansoni.

Front. Immunol., https://doi.org/10.3389/fimmu.2021.635622(link is external)

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Berni, F., E. Kalfopoulou, A.M. Gimeno Cardells, F. Carboni, D. van der Es, F. Romero-Saavedra, D. Laverde, K. Miklic, S. Malic, T.L. Rovis, S. Jonjic, S. Ali, H.S. Overkleeft, C.H. Hokke, A. van Diepen, R. Adamo, J. Jiménez-Barbero, G.A. van der Marel, J. Huebner, and J.D.C. Codée. 2021.

Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid.

ACS Chem Biol. https://doi.org/10.1021/acschembio.1c00422(link is external)

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Deschler, S., J. Kager, J. Erber, L. Fricke, P. Koyumdzhieva, A. Georgieva, T. Lahmer, J.R. Wiessner, F. Voit, J. Schneider, J. Horstmann, R. Iakoubov, M. Treiber, C. Winter, J. Ruland, D.H. Busch, P.A. Knolle, U. Protzer, C.D. Spinner, R.M. Schmid, M. Quante, and K. Bottcher. 2021.

Mucosal-Associated Invariant T (MAIT) Cells Are Highly Activated and Functionally Impaired in COVID-19 Patients.

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Habib M, Esen M, Honkpehedji J, Klug SJ, Lobmaier S, Vogg K, Bustinduy AL, Ullrich A, Reinhard-Rupp J, Akim Adegnika A, Prazeres da Costa C. 2021

The Challenges in Women’s Health in sub-Saharan Africa: Lessons learned from an integrative multistakeholder workshop in Gabon.

J Glob Health 2021 Sep 4;11:02002. doi: 10.7189/jogh.11.02002(link is external). eCollection 2021.


Habib M, Lange U, Ludwig S, Prazeres da Costa C. 2021

The Impact of the COVID-19 Pandemic on Pregnancy, Birth and Sexual & Reproductive Health and Rights – Perspectives from Germany and Somalia.

J Glob Health 2021 Sep 4;11:03085. doi: 10.7189/jogh.11.03085(link is external). eCollection 2021.


Heim, M., T. Lahmer, S. Rasch, S. Kriescher, W. Berg-Johnson, K. Fuest, B. Kapfer, G. Schneider, C.D. Spinner, F. Geisler, J.R. Wiessner, K. Rothe, S. Feihl, and A. Ranft. 2021.

Rapid clinical evolution for COVID-19 translates into early hospital admission and unfavourable outcome: a preliminary report.

Multidiscip Respir Med. 16:744. https://doi.org/10.4081/mrm.2021.744(link is external)

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Jarosch S., Köhlen J, Sarker R.S.J. , Steiger K. , Janssen K.P. ,Christians A. , Hennig C. , Holler  E., E. D'Ippolito, D.H. Busch. 2021

Multiplexed imaging and automated signal quantification in formalin-fixed paraffin-embedded tissues by ChipCytometry.

Cell Rep Methods., 2021 Oct 27;1(7):100104. https://doi.org/10.1016/j.crmeth.2021.100104(link is external)

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Kalin, R.E., L. Cai, Y. Li, D. Zhao, H. Zhang, J. Cheng, W. Zhang, Y. Wu, K. Eisenhut, P. Janssen, L. Schmitt, W. Enard, F. Michels, C. Fluh, M. Hou, S.V. Kirchleitner, S. Siller, M. Schiemann, I. Andra, E. Montanez, C. Giachino, V. Taylor, M. Synowitz, J.C. Tonn, L. von Baumgarten, C. Schulz, I. Hellmann, and R. Glass. 2021

TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression.

Cell Syst. 2021.12:248-262 e247. https://doi.org/10.1016/j.cels.2021.01.002(link is external)

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Kretschmer, L., D.H. Busch, and V.R. Buchholz. 2021.

A Single-Cell Perspective on Memory T-Cell Differentiation.

Cold Spring Harb Perspect Biol.

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Lacorcia, M., S. Bhattacharjee, K. Laubhahn, F. Alhamdan, M. Ram, A. Muschaweckh, D.P. Potaczek, A. Kosinska, H. Garn, U. Protzer, H. Renz, and C. Prazeres da Costa. 2021.

Fetomaternal immune cross talk modifies T-cell priming through sustained changes to DC function.

The Journal of allergy and clinical immunology. https://doi.org/10.1016/j.jaci.2021.02.031(link is external)

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Lahmer, T., S. Kriescher, A. Herner, K. Rothe, C.D. Spinner, J. Schneider, U. Mayer, M. Neuenhahn, D. Hoffmann, F. Geisler, M. Heim, G. Schneider, R.M. Schmid, W. Huber, and S. Rasch. 2021.

Invasive pulmonary aspergillosis in critically ill patients with severe COVID-19 pneumonia: Results from the prospective AspCOVID-19 study.

PLoS One. https://doi.org/10.1371/journal.pone.0238825(link is external)

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Mathewson, N.D., O. Ashenberg, I. Tirosh, S. Gritsch, E.M. Perez, S. Marx, L. Jerby-Arnon, R. Chanoch-Myers, T. Hara, A.R. Richman, Y. Ito, J. Pyrdol, M. Friedrich, K. Schumann, M.J. Poitras, P.C. Gokhale, L.N. Gonzalez Castro, M.E. Shore, C.M. Hebert, B. Shaw, H.L. Cahill, M. Drummond, W. Zhang, O. Olawoyin, H. Wakimoto, O. Rozenblatt-Rosen, P.K. Brastianos, X.S. Liu, P.S. Jones, D.P. Cahill, M.P. Frosch, D.N. Louis, G.J. Freeman,  K.L. Ligon, A. Marson, E.A. Chiocca, D.A. Reardon, A. Regev, M.L. Suva, and K.W. Wucherpfennig. 2021.

Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.

Cell. 184:1281-1298 e1226. https://doi.org/10.1016/j.cell.2021.01.022(link is external)

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Mejías-Luque, R. 2021.

Senescence: A Novel Driver of Helicobacter pylori-Induced Gastric Atrophy.

Cell Mol Gastroenterol Hepatol. 11:887-888. https://doi.org/10.1016/j.jcmgh.2020.12.005(link is external)

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Mitsdörffer, M., G. Di Liberto, S. Dötsch, C. Sie, I. Wagner, M. Pfaller, M. Kreutzfeldt, S. Fräßle, L. Aly, B. Knier, D.H. Busch, D. Merkler, and T. Korn. 2021.

Formation and immunomodulatory function of meningeal B-cell aggregates in progressive CNS autoimmunity.

Brain, awab235, (link is external)https://doi.org/10.1093/brain/awab235(link is external)
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Müller  T.R. , Jarosch  S. , Hammel  M. , Leube  J. , Grassmann  S. , Bernard  B. , Effenberger  M. , Andrä  I. , Zeeshan Chaudhry  M. , Käuferle  T. , Malo  A. , Cicin-Sain  L. , Steinberger  P. , Feuchtinger  T.  , Protzer  U. , Schumann  K. , Neuenhahn  M. , Schober  K. , Busch  D.H. 2021

Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy

Cell Rep Med. 2021 Aug 17;2(8):100374. PMID: 34467251, PMCID: PMC8385324 (link is external), DOI: 10.1016/j.xcrm.2021.100374 (link is external)

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Neumeyer, V., A. Brutau-Abia, M. Allgäuer, N. Pfarr, W. Weichert, C. Falkeis-Veits, E. Kremmer, M. Vieth, M. Gerhard, and R. Mejías-Luque. 2021.

Loss of RNF43 Function Contributes to Gastric Carcinogenesis by Impairing DNA Damage Response.

Cell Mol Gastroenterol Hepatol. 11:1071-1094. https://doi.org/10.1016/j.jcmgh.2020.11.005(link is external)

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Rothe, K., S. Feihl, J. Schneider, F. Wallnofer, M. Wurst, M. Lukas, M. Treiber, T. Lahmer, M. Heim, M. Dommasch, B. Waschulzik, A. Zink, C. Querbach, D.H. Busch, R.M. Schmid, G. Schneider, and C.D. Spinner. 2021.

Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship.

Eur J Clin Microbiol Infect Dis. 40pages 859–869

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Rothe, K., S. Rasch, N. Wantia, A. Poszler, J. Ulrich, C. Schlag, W. Huber, R.M. Schmid, D.H. Busch, and T. Lahmer. 2021.

Aspergillus fumigatus cholangitis in a patient with cholangiocarcinoma: case report and review of the literature.

Infection. 49, 159–164

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Sasse, D., C.D. Spinner, K. Rothe, J. Schneider, J. Gaa, and S. Wurstle. 2021.

Treatment of intestinal tuberculosis with small bowel perforation: a case report.

J Med Case Rep. 15:144.

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Schambeck  S.E., Crowell  C.S.,  Wagner  K.I., D'Ippolito  E., Burrell  T., Mijočević  H. , Protzer  U., Busch  D.H., Gerhard  M., Poppert  H., Beyer  H. 2021

Phantosmia, Parosmia, and Dysgeusia Are Prolonged and Late-Onset Symptoms of COVID-19

J Clin Med. 2021 Nov 12;10(22):5266. PMID: 34830550 PMCID: PMC8618742 (link is external) DOI: 10.3390/jcm10225266 (link is external)

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Schneider, J., H. Mijocevic, K. Ulm, B. Ulm, S. Weidlich, S. Wurstle, K. Rothe, M. Treiber, R. Iakoubov, U. Mayr, T. Lahmer, S. Rasch, A. Herner, E. Burian, F. Lohofer, R. Braren, M.R. Makowski, R.M. Schmid, U. Protzer, C. Spinner, and F. Geisler. 2021.

SARS-CoV-2 serology increases diagnostic accuracy in CT-suspected, PCR-negative COVID-19 patients during pandemic.

Respir Res. 22:119. https://doi.org/10.1186/s12931-021-01717-9

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Silvestre-Roig, C., P. Lemnitzer, J. Gall, S. Schwager, A. Toska, L. Yvan-Charvet, M. Detmar, and O. Soehnlein. 2021.

Arterial Delivery of VEGF-C Stabilizes Atherosclerotic Lesions.

Circ Res. 128:284-286. https://doi.org/10.1161/CIRCRESAHA.120.317186(link is external)

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Stief, T.A., T. Kaeuferle, T.R. Müller, M. Doring, L.M. Jablonowski, K. Schober, J. Feucht, K.M. Dennehy, S. Willier, F. Blaeschke, R. Handgretinger, P. Lang, D.H. Busch,
and T. Feuchtinger. 2021.

Protective T-cell receptor identification for orthotopic reprogramming of immunity in refractory virus infections.

Mol Ther. https://doi.org/10.1016/j.ymthe.2021.05.021(link is external)

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Vejzagic, N., U.F. Prodjinotho, N. El-Khafif, R. Huang, A. Simeonov, T. Spangenberg, and C. Prazeres da Costa. 2021.

Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium.

PLoS Negl Trop Dis. https://doi.org/10.1371/journal.pntd.0009432(link is external)

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Wagner, L.F., I. Lanzl, K. Rothe, J. Schneider, A. Zink, D. Zapp, C. Schwerdtfeger, M. Lee, S. Weidlich, M. Neuenhahn, D. Loos, and C.D. Spinner. 2021.

Clinical and Ophthalmological Characteristics of Ocular Syphilis in a Retrospective Tertiary Hospital Cohort.

Sex Transm Dis. 48:436-442. doi: 10.1097/OLQ.0000000000001329

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Weickert, M.T., J.S. Hecker, M.C. Buck, C. Schreck, J. Riviere, M. Schiemann, K. Schallmoser, F. Bassermann, D. Strunk, R.A.J. Oostendorp, and K.S. Gotze. 2021.

Bone marrow stromal cells from MDS and AML patients show increased adipogenic potential with reduced Delta-like-1 expression.

Sci Rep. 11:5944. DOI: 10.1038/s41598-021-85122-8 (link is external)

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Wiedemann, G.M., J. Schneider, M. Verbeek, B. Konukiewitz, C.D. Spinner, H. Einwachter, R.M. Schmid, and K. Rothe. 2021.

An Eschar-like souvenir from a journey to Colombia: Ecthyma gangrenosum as a differential diagnosis of tropical diseases in immunocompromised patients - a case report.

BMC Infect Dis. 21:344. https://doi.org/10.1186/s12879-021-05998-9

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