Gerhard
Group leader
Assistant Director
Fax: +49 89 4140-4868
Sprechzeiten:
- no information -
- no information -
Mejías-Luque
Group leader
Fax: +49 89 4140-4131
Sprechzeiten:
Telefon Labor: +49 89 4140-4126
Telefon Labor: +49 89 4140-4126
Mechanisms of host-pathogen interaction during chronic infection, inflammation and carcinogenesis
Bild: Susanne Dürr, 2023
Our research group is working on the mechanisms of tumor development in the gastrointestinal tract, especially during chronic inflammation elicited by Helicobacter pylori infection in the stomach. Another focus is the deregulation of the Wnt signaling pathway during bacterial infection in the intestine and colon. In parallel, we are interested in identifying targets to develop novel prophylactic approaches and therapeutic strategies for H. pylori infection and stomach cancer.
*dieser Inhalt ist nur auf Englisch verfügbar*
- The roles of tissue resident T cells during H. pylori infection and after immunization
- Characterization of CD8+T cell responses during H. pylori infection
- The in-vivo function of gamma-glutamyltransferase, an essential virulence factor of Helicobacter pylori during colonization and immune response
- Helicobacter infection and microbiota-dependent colonic inflammation and pathogenesis
- H. pylori interaction with CEACAM receptors
- Characterization and CRISPR-dissection of human regulatory T cells in gastric cancer
- microbiome sequencing facility
- microbiome changes upon H. pylori infection in vivo