Information & news

Game-changing research collaboration starts:

Vax2Muc will pave the way for next-generation vaccines against gastrointestinal mucosal pathogens

The constant rise in antimicrobial resistance (AMR) has a major impact on global public health, urgently requiring novel strategies to prevent and treat bacterial infections. The development of effective vaccines represents an attractive cost-effective alternative to novel antibiotics and would be a game changer for patients. For many bacterial infections, especially those occurring on mucosal sites, no effective vaccines exist. Helicobacter pylori (H. pylori), a pathogen residing in the stomach, is the cause of the most common chronic bacterial infection, affecting half of the world´s population, with a high risk to progress into gastric cancer...


How immune cells overcome exhaustion

Researchers have discovered a new population of immune cells which are critical in maintaining the immune response against chronic infections and cancer. This population of T cells also mediates the response to immunotherapy..

 Dr. med. Veit R. Buchholz and Dr. med. Lorenz Kretschmer

Andreas Heddergott / TUM

Awards for Anna Ralser and Verena Friedrich

On the“14th International Workshop on Pathogenesis and Host Response in Helicobacter Infections”  in Helsingør, Denmark on June 29th - July 2nd, 2022, Dr. med. Univ. Anna Ralser (second left) was awarded  "Best Overall Presentation" prize for her presentation "Helicobacter pylori promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature."

The "Best Poster" prize went to Dr. rer. nat. Verena Friedrich (third left) for her poster "Tackling Helicobacter pylori infection by a pre-clinical, prophylactic vaccination strategy"

Lymphocyte Engineering for Therapeutic Synthetic Immunity

Adoptive T cell therapy has advanced to become a distinguished and rapidly evolving translational research field in modern medicine....

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News from the da Costa team

We are proud to be featured in the latest article of Research in Bavaria!

Parasitic worms (helminths) outsmart the human immunesystem and weaken its response after millennia of co-evolution and adaptation.

Learn more about why we need more global and connected research on helminths:

How the immune system remembers viruses

Link: Press release TUM(link is external)

For a person to acquire immunity to a disease, T cells must develop into memory cells after contact with the pathogen. Until now, the number of cells that do this was believed to depend above all on the magnitude of the initial immune response. A team of researchers at the Technical University of Munich (TUM) has now called this into question.

"Faszination Forschung"


Link: Healthy lives for all(link is external)

Worm infections are widespread in low-income coun­tries. Clarissa Prazeres da Costa investigates how these neglected tropical diseases affect the immune system.

"Faszination Forschung"


Link: Global Health Needs a Multidisciplinary Approach(link is external)

“Ensuring healthy lives for all” is one of the United Nations’ Sustainable Development Goals. The Center for Global Health at the TUM School of Medicine is addressing these topics

New member of the Leopoldina

Professor Dirk Busch, Head of the Institute of Medical Microbiology at the Klinikum rechts der Isar, has been appointed a member of the National Academy of Sciences Leopoldina.

The long-established scientific society in Halle has approximately 1,500 members. Now another physician from the Klinikum rechts der Isar has joined. At the Annual Symposium of the Life Sciences on May 23, the Leopoldina will officially admit Professor Dirk Busch to its circle. read more...(link is external)

News from CGH

The consortial project HELMVIT (“Impact of maternal helminth infection on Vitamin D regulation and on the immune system of the infant”) was kicked-off in January 2019, in Lambaréné, Gabon. This project is coordinated by Prof. Clarissa Prazeres da Costa, co-director of the Center for Global Health, Institute for Medical Microbiology, Immunology and Hygiene of TUM and collaboration partners are Prof. Akim Adegnika (CERMEL) and Dr. Meral Esen (Institute for Tropical Medicine, University of Tübingen). The consortium is funded for three years by the DFG within the call “German-African Cooperation Projects in Infectiology”.

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